Which statement about screening in neurofibromatosis type 2 is true?

• A. Eye examinations should be performed annually
• B. MRI of the brain is required yearly
• C. Neither eye exams nor brain imaging are recommended yearly
• D. Both eye exams and brain MRI are unnecessary

Answer: (B)

In neurofibromatosis type 2, the biggest risk is development of intracranial tumors, especially bilateral vestibular schwannomas, which can progress silently. Because these tumors can grow before symptoms appear, regular brain imaging is essential to catch them early and guide treatment to protect hearing and balance. While eye problems can occur in NF2, annual eye exams do not replace the need for CNS tumor surveillance, and the idea that neither or both modalities are unnecessary doesn’t fit the disease’s risks. Therefore, yearly brain MRI is the best-supported screening approach.