True or False: Steroids and antihistamines can be used to prevent anaphylaxis from bee stings.

• A. True
• B. Sometimes
• C. Not effective
• D. False

Answer: (D)

Anaphylaxis is a rapid, life-threatening reaction driven by multiple mediators released from mast cells and basophils. Preventing a bee-sting anaphylactic reaction isn’t achieved by antihistamines or steroids, because to stop the progression you need to counter the several pathways that cause airway swelling, bronchoconstriction, and low blood pressure. Antihistamines block histamine but don’t prevent the full cascade, and steroids act slowly and are not reliable for preventing acute anaphylaxis. The agent that truly prevents future severe reactions to bee stings is venom immunotherapy, which desensitizes the immune system to the venom. In contrast, carrying an epinephrine auto-injector remains essential for immediate treatment if a reaction occurs. So the statement is not correct.