Aminoglycosides (gentamicin) are contraindicated in pregnancy.

• A. True
• B. False
• C. Not sure
• D. Only in the first trimester

Answer: (A)

Aminoglycosides have fetal toxicity risks, so they are avoided during pregnancy. Gentamicin crosses the placenta and can damage the developing fetus, particularly the inner ear and kidneys. This can lead to sensorineural deafness in the newborn and potential renal impairment. For that reason, these antibiotics are considered contraindicated in pregnancy unless no safer, effective alternative exists and the infection is life-threatening to the mother or fetus. In routine pregnancy infections, safer options like beta-lactams or certain macrolides are preferred.